BDBM149693 US8975267, 35

SMILES: CSc1ncc2ccc3c(cn(C4CCNCC4)c3c2n1)C(N)=O

InChI Key: InChIKey=ZWVHBACWMIHSNL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 149693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM149693 (US8975267, 35) Show SMILES CSc1ncc2ccc3c(cn(C4CCNCC4)c3c2n1)C(N)=O Show InChI InChI=1S/C17H19N5OS/c1-24-17-20-8-10-2-3-12-13(16(18)23)9-22(15(12)14(10)21-17)11-4-6-19-7-5-11/h2-3,8-9,11,19H,4-7H2,1H3,(H2,18,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	3.0	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...				US Patent US8975267 (2015) BindingDB Entry DOI: 10.7270/Q29C6W41
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM149693 (US8975267, 35) Show SMILES CSc1ncc2ccc3c(cn(C4CCNCC4)c3c2n1)C(N)=O Show InChI InChI=1S/C17H19N5OS/c1-24-17-20-8-10-2-3-12-13(16(18)23)9-22(15(12)14(10)21-17)11-4-6-19-7-5-11/h2-3,8-9,11,19H,4-7H2,1H3,(H2,18,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...				US Patent US8975267 (2015) BindingDB Entry DOI: 10.7270/Q29C6W41
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM149693 (US8975267, 35) Show SMILES CSc1ncc2ccc3c(cn(C4CCNCC4)c3c2n1)C(N)=O Show InChI InChI=1S/C17H19N5OS/c1-24-17-20-8-10-2-3-12-13(16(18)23)9-22(15(12)14(10)21-17)11-4-6-19-7-5-11/h2-3,8-9,11,19H,4-7H2,1H3,(H2,18,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	3.0	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...				US Patent US8975267 (2015) BindingDB Entry DOI: 10.7270/Q29C6W41
					More data for this Ligand-Target Pair