BDBM149710 US8975409, Example 38
SMILES: CC(C)CC1(O)CCN(CC1)C(=O)Nc1cc(Oc2ccc(F)cc2)cc(c1)C(=O)Oc1ccc(cc1)C(C)(C)C(O)=O
InChI Key: InChIKey=HCNPUNDFLQNIOB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 2 (S1P2) (Rattus norvegicus (Rat)) | BDBM149710 (US8975409, Example 38) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.2 | 37 |
ONO Pharmaceutical Co., Ltd. US Patent | Assay Description Chinese hamster ovary (CHO) cells overexpressing the human S1P2 gene were cultured in a Ham's F12 medium containing 10% fetal bovine serum (FBS), an ... | US Patent US8975409 (2015) BindingDB Entry DOI: 10.7270/Q2X34W60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM149710 (US8975409, Example 38) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | 7.2 | 37 |
ONO Pharmaceutical Co., Ltd. US Patent | Assay Description Chinese hamster ovary (CHO) cells overexpressing the human S1P2 gene were cultured in a Ham's F12 medium containing 10% fetal bovine serum (FBS), an ... | US Patent US8975409 (2015) BindingDB Entry DOI: 10.7270/Q2X34W60 | |||||||||||
More data for this Ligand-Target Pair |