BDBM15013 2,4-diethyl 5-(hydroxymethyl)-3-methyl-1H-pyrrole-2,4-dicarboxylate::Pyrrole Analogue 3

SMILES: CCOC(=O)c1[nH]c(CO)c(C(=O)OCC)c1C

InChI Key: InChIKey=MJDIWVWPQXHGAJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM15013 (2,4-diethyl 5-(hydroxymethyl)-3-methyl-1H-pyrrole-...) Show SMILES CCOC(=O)c1[nH]c(CO)c(C(=O)OCC)c1C Show InChI InChI=1S/C12H17NO5/c1-4-17-11(15)9-7(3)10(12(16)18-5-2)13-8(9)6-14/h13-14H,4-6H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...				Biochemistry 44: 9430-40 (2005) Article DOI: 10.1021/bi0500628 BindingDB Entry DOI: 10.7270/Q2BV7DV5
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM15013 (2,4-diethyl 5-(hydroxymethyl)-3-methyl-1H-pyrrole-...) Show SMILES CCOC(=O)c1[nH]c(CO)c(C(=O)OCC)c1C Show InChI InChI=1S/C12H17NO5/c1-4-17-11(15)9-7(3)10(12(16)18-5-2)13-8(9)6-14/h13-14H,4-6H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...				Biochemistry 44: 9430-40 (2005) Article DOI: 10.1021/bi0500628 BindingDB Entry DOI: 10.7270/Q2BV7DV5
					More data for this Ligand-Target Pair