null
SMILES: COc1ccc(COc2nc(ncc2C(=O)NCc2ccc(F)cc2)N2CC3CC3C2)cc1Cl
InChI Key: InChIKey=RWUZHHNNVVOHSY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM150181 (US8980904, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0750 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Xuanzhu Pharma Co., Ltd. US Patent | Assay Description A sample to be tested is precisely weighed, dissolved by adding DMSO, mixed sufficiently to form 10 mM solution. The above mother solution is diluted... | US Patent US8980904 (2015) BindingDB Entry DOI: 10.7270/Q24M9389 | |||||||||||
More data for this Ligand-Target Pair |