BDBM150229 US8980906, 31

SMILES: COc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(Cc5[nH]c(=O)c(cc5C[C@@]34O)C(N)=O)c2c1

InChI Key:

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM150229 (US8980906, 31) Show SMILES COc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(Cc5[nH]c(=O)c(cc5C[C@@]34O)C(N)=O)c2c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...				US Patent US8980906 (2015) BindingDB Entry DOI: 10.7270/Q2W37V15
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM150229 (US8980906, 31) Show SMILES COc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(Cc5[nH]c(=O)c(cc5C[C@@]34O)C(N)=O)c2c1 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.59E+3	-7.76	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membran...				US Patent US8980906 (2015) BindingDB Entry DOI: 10.7270/Q2W37V15
					More data for this Ligand-Target Pair