BDBM150287 US8987242, 67

SMILES: CC(C)(C)c1ccc(cc1)N1CCO[C@H]([C@@H](O)C(=O)Nc2ccc(cc2F)C(N)=N)C1=O

InChI Key: InChIKey=YRRLJODQLNZJFI-RTBURBONSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM150287 (US8987242, 67) Show SMILES CC(C)(C)c1ccc(cc1)N1CCO[C@H]([C@@H](O)C(=O)Nc2ccc(cc2F)C(N)=N)C1=O |r| Show InChI InChI=1S/C23H27FN4O4/c1-23(2,3)14-5-7-15(8-6-14)28-10-11-32-19(22(28)31)18(29)21(30)27-17-9-4-13(20(25)26)12-16(17)24/h4-9,12,18-19,29H,10-11H2,1-3H3,(H3,25,26)(H,27,30)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair