BDBM150297 US8987242, aa151

SMILES: Nc1noc2cc(NC(=O)C(O)[C@H]3OCCN(C3=O)c3ccc(cc3)S(F)(F)(F)(F)F)ccc12

InChI Key: InChIKey=ROYDDLHHUNODQH-OEMAIJDKSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM150297 (US8987242, aa151) Show SMILES Nc1noc2cc(NC(=O)C(O)[C@H]3OCCN(C3=O)c3ccc(cc3)S(F)(F)(F)(F)F)ccc12 Show InChI InChI=1S/C19H17F5N4O5S/c20-34(21,22,23,24)12-4-2-11(3-5-12)28-7-8-32-16(19(28)31)15(29)18(30)26-10-1-6-13-14(9-10)33-27-17(13)25/h1-6,9,15-16,29H,7-8H2,(H2,25,27)(H,26,30)/t15?,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair