BDBM150615 US10238633, Example 289::US8987249, 289::US9713606, 289

SMILES: CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1

InChI Key: InChIKey=WONAWGLRVBZQLT-VKDGWMQASA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 150615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM150615 (US10238633, Example 289 | US8987249, 289 | US97136...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H30FN5O3/c1-31-8-10-32(11-9-31)26(34)23-7-6-22(35-23)17-3-2-16(21(27)14-17)12-20(15-28)30-25(33)24-18-4-5-19(13-18)29-24/h2-3,6-7,14,18-20,24,29H,4-5,8-13H2,1H3,(H,30,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8987249 (2015) BindingDB Entry DOI: 10.7270/Q2KP80WG
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM150615 (US10238633, Example 289 | US8987249, 289 | US97136...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H30FN5O3/c1-31-8-10-32(11-9-31)26(34)23-7-6-22(35-23)17-3-2-16(21(27)14-17)12-20(15-28)30-25(33)24-18-4-5-19(13-18)29-24/h2-3,6-7,14,18-20,24,29H,4-5,8-13H2,1H3,(H,30,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q22R3TZF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM150615 (US10238633, Example 289 | US8987249, 289 | US97136...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H30FN5O3/c1-31-8-10-32(11-9-31)26(34)23-7-6-22(35-23)17-3-2-16(21(27)14-17)12-20(15-28)30-25(33)24-18-4-5-19(13-18)29-24/h2-3,6-7,14,18-20,24,29H,4-5,8-13H2,1H3,(H,30,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....				US Patent US9713606 (2017) BindingDB Entry DOI: 10.7270/Q21G0P8M
					More data for this Ligand-Target Pair