BDBM150725 4‐bromo‐2‐{[3‐ (trifluoromethyl)phenyl]carbamoyl}phenyl diethyl phosphate (5)

SMILES: CCOP(=O)(OCC)Oc1ccc(Br)cc1C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=JEQNCBYXIIXIBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM150725 (4‐bromo‐2‐{[3‐ (trifluorom...) Show SMILES CCOP(=O)(OCC)Oc1ccc(Br)cc1C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H18BrF3NO5P/c1-3-26-29(25,27-4-2)28-16-9-8-13(19)11-15(16)17(24)23-14-7-5-6-12(10-14)18(20,21)22/h5-11H,3-4H2,1-2H3,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Charles University in Prague					Assay Description The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ...				Bioorg Chem 58: 48-52 (2015) Article DOI: 10.1016/j.bioorg.2014.11.005 BindingDB Entry DOI: 10.7270/Q26D5RQ1
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM150725 (4‐bromo‐2‐{[3‐ (trifluorom...) Show SMILES CCOP(=O)(OCC)Oc1ccc(Br)cc1C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H18BrF3NO5P/c1-3-26-29(25,27-4-2)28-16-9-8-13(19)11-15(16)17(24)23-14-7-5-6-12(10-14)18(20,21)22/h5-11H,3-4H2,1-2H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Charles University in Prague					Assay Description The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ...				Bioorg Chem 58: 48-52 (2015) Article DOI: 10.1016/j.bioorg.2014.11.005 BindingDB Entry DOI: 10.7270/Q26D5RQ1
					More data for this Ligand-Target Pair