BDBM150769 2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(biphenyl-4-yl)-ethanone (2)

SMILES: O=C(CSc1nnc2c(n1)[nH]c1ccccc21)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=GDBZIUKVGZBIRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM150769 (2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(bip...) Show SMILES O=C(CSc1nnc2c(n1)[nH]c1ccccc21)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H16N4OS/c28-20(17-12-10-16(11-13-17)15-6-2-1-3-7-15)14-29-23-25-22-21(26-27-23)18-8-4-5-9-19(18)24-22/h1-13H,14H2,(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.84E+4	n/a	n/a	n/a	n/a	n/a	310.15
Hazara University					Assay Description Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat...				Bioorg Chem 58: 81-7 (2015) Article DOI: 10.1016/j.bioorg.2014.12.001 BindingDB Entry DOI: 10.7270/Q2JQ0ZR8
					More data for this Ligand-Target Pair