BDBM151022 US8987257, 35

SMILES: OCc1ccccc1-c1nc2c(nc(nc2[nH]1)N1CCOCC1)N1CCOCC1

InChI Key: InChIKey=UXJUBJNTKJPGOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM151022 (US8987257, 35) Show SMILES OCc1ccccc1-c1nc2c(nc(nc2[nH]1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C20H24N6O3/c27-13-14-3-1-2-4-15(14)17-21-16-18(22-17)23-20(26-7-11-29-12-8-26)24-19(16)25-5-9-28-10-6-25/h1-4,27H,5-13H2,(H,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description PI3K KinaseGlo assay: 50 mL of compound dilutions were dispensed onto black 384-well low volume Non Binding Styrene (NBS) plates (Costar Cat. No. NBS...				US Patent US8987257 (2015) BindingDB Entry DOI: 10.7270/Q2S75F2B
					More data for this Ligand-Target Pair