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BDBM15106 3-[(2S)-2-amino-3-{3-[(E)-2-(pyridin-4-yl)ethenyl]phenoxy}propyl]-1H-indole::trans-bispyridinylethylene analog 6a

SMILES: N[C@H](COc1cccc(\C=C\c2ccncc2)c1)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=TVFSXXGRMGACEZ-SHBDEGQCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15106   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase B (Akt 1)


(Homo sapiens (Human))		BDBM15106
PNG
(3-[(2S)-2-amino-3-{3-[(E)-2-(pyridin-4-yl)ethenyl]...)
Show SMILES N[C@H](COc1cccc(\C=C\c2ccncc2)c1)Cc1c[nH]c2ccccc12 |r|
Show InChI InChI=1S/C24H23N3O/c25-21(15-20-16-27-24-7-2-1-6-23(20)24)17-28-22-5-3-4-19(14-22)9-8-18-10-12-26-13-11-18/h1-14,16,21,27H,15,17,25H2/b9-8+/t21-/m0/s1
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 1679-85 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.017
BindingDB Entry DOI: 10.7270/Q23F4MWN
More data for this
Ligand-Target Pair