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BDBM151423 US8987314, B234

SMILES: COCCS(=O)(=O)C(C(=O)NCc1cc(C)no1)c1nc2ccc(cc2s1)-c1ccccc1

InChI Key: InChIKey=MKUWDZXEVXLOIX-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151423   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151423
PNG
(US8987314, B234)
Show SMILES COCCS(=O)(=O)C(C(=O)NCc1cc(C)no1)c1nc2ccc(cc2s1)-c1ccccc1
Show InChI InChI=1/C23H23N3O5S2/c1-15-12-18(31-26-15)14-24-22(27)21(33(28,29)11-10-30-2)23-25-19-9-8-17(13-20(19)32-23)16-6-4-3-5-7-16/h3-9,12-13,21H,10-11,14H2,1-2H3,(H,24,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.5n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM151423
PNG
(US8987314, B234)
Show SMILES COCCS(=O)(=O)C(C(=O)NCc1cc(C)no1)c1nc2ccc(cc2s1)-c1ccccc1
Show InChI InChI=1/C23H23N3O5S2/c1-15-12-18(31-26-15)14-24-22(27)21(33(28,29)11-10-30-2)23-25-19-9-8-17(13-20(19)32-23)16-6-4-3-5-7-16/h3-9,12-13,21H,10-11,14H2,1-2H3,(H,24,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.90n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair