BDBM15144 5-(5-{[(2S)-2-amino-5-phenylpentyl]oxy}pyridin-3-yl)-3-methyl-1H-indazole::5-indazolyl pyridine 11m

SMILES: Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)CCCc2ccccc2)c1

InChI Key: InChIKey=KSGOTVTVGWSRAU-NRFANRHFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase B (Akt 1) (Homo sapiens (Human))	BDBM15144 (5-(5-{[(2S)-2-amino-5-phenylpentyl]oxy}pyridin-3-y...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)CCCc2ccccc2)c1 |r| Show InChI InChI=1S/C24H26N4O/c1-17-23-13-19(10-11-24(23)28-27-17)20-12-22(15-26-14-20)29-16-21(25)9-5-8-18-6-3-2-4-7-18/h2-4,6-7,10-15,21H,5,8-9,16,25H2,1H3,(H,27,28)/t21-/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	70.6	-9.65	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair