BDBM151493 US8987314, B304

SMILES: CO[C@H]1CCN(C1)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F

InChI Key: InChIKey=IVYYRECVZKVMSW-YDNXMHBPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151493 (US8987314, B304) Show SMILES CO[C@H]1CCN(C1)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F |r| Show InChI InChI=1S/C26H29F3N4O7S3/c1-40-19-8-11-33(15-19)25(35)17-4-2-16(3-5-17)18-6-7-20-21(14-18)41-24(32-20)22(23(34)31-10-13-43(30,38)39)42(36,37)12-9-26(27,28)29/h2-7,14,19,22H,8-13,15H2,1H3,(H,31,34)(H2,30,38,39)/t19-,22?/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16.6	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151493 (US8987314, B304) Show SMILES CO[C@H]1CCN(C1)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F |r| Show InChI InChI=1S/C26H29F3N4O7S3/c1-40-19-8-11-33(15-19)25(35)17-4-2-16(3-5-17)18-6-7-20-21(14-18)41-24(32-20)22(23(34)31-10-13-43(30,38)39)42(36,37)12-9-26(27,28)29/h2-7,14,19,22H,8-13,15H2,1H3,(H,31,34)(H2,30,38,39)/t19-,22?/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair