BDBM151521 US8987314, B332

SMILES: NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(c1)C(=O)N1CCC(O)CC1)S(=O)(=O)CCC(F)(F)F

InChI Key: InChIKey=XDPSJFCZCTUSSD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151521 (US8987314, B332) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(c1)C(=O)N1CCC(O)CC1)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C26H29F3N4O7S3/c27-26(28,29)8-12-42(37,38)22(23(35)31-9-13-43(30,39)40)24-32-20-5-4-17(15-21(20)41-24)16-2-1-3-18(14-16)25(36)33-10-6-19(34)7-11-33/h1-5,14-15,19,22,34H,6-13H2,(H,31,35)(H2,30,39,40)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	137	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151521 (US8987314, B332) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(c1)C(=O)N1CCC(O)CC1)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C26H29F3N4O7S3/c27-26(28,29)8-12-42(37,38)22(23(35)31-9-13-43(30,39)40)24-32-20-5-4-17(15-21(20)41-24)16-2-1-3-18(14-16)25(36)33-10-6-19(34)7-11-33/h1-5,14-15,19,22,34H,6-13H2,(H,31,35)(H2,30,39,40)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair