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SMILES: FC(F)(C1CC1)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1Cl

InChI Key: InChIKey=BQYTUZXGABHMCN-UHFFFAOYSA-M

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151749   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151749
PNG
(US8987445, 185)
Show SMILES FC(F)(C1CC1)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1Cl
Show InChI InChI=1S/C30H25ClF2N2O4S.Na/c31-26-15-18(5-14-25(26)30(32,33)22-10-11-22)17-35(40(38,39)23-12-8-20(9-13-23)29(36)37)28-27(19-6-7-19)24-4-2-1-3-21(24)16-34-28;/h1-5,8-9,12-16,19,22H,6-7,10-11,17H2,(H,36,37);/q;+1/p-1
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Similars
US Patent
n/an/a 1.20n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair