BDBM152289 US8993557, 33

SMILES: Oc1c(ccn(CC(F)(F)F)c1=O)C(=O)NC1CCN(CC1)c1ccc(F)cc1

InChI Key: InChIKey=HOQBIGXCMYBDET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM152289 (US8993557, 33) Show SMILES Oc1c(ccn(CC(F)(F)F)c1=O)C(=O)NC1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H19F4N3O3/c20-12-1-3-14(4-2-12)25-8-5-13(6-9-25)24-17(28)15-7-10-26(11-19(21,22)23)18(29)16(15)27/h1-4,7,10,13,27H,5-6,8-9,11H2,(H,24,28)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US8993557 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M1Z
					More data for this Ligand-Target Pair