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SMILES: CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=WVUXBWHQPQQYQQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152643   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Dengue virus 2 (Virus))		BDBM152643
PNG
(2-(4-(4-Methylpiperazin-1-ylsulphonyl)phenyl)isoin...)
Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C30H23N5O2S/c36-35(37)22-15-13-21(14-16-22)34-30(38)33-20-11-9-19(10-12-20)29(25-17-31-27-7-3-1-5-23(25)27)26-18-32-28-8-4-2-6-24(26)28/h1-18,29,31-32H,(H2,33,34,38)
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Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.5n/a



Birla Institute of Technology



Assay Description
To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...

Bioorg Chem 62: 74-82 (2015)


Article DOI: 10.1016/j.bioorg.2015.07.005
BindingDB Entry DOI: 10.7270/Q2VT1QTG
More data for this
Ligand-Target Pair