BDBM152644 4-(1,3-Dioxoisoindolin-2-yl)-N-phenylbenzenesulphonamide (7)

SMILES: O=C1N(C(=O)c2ccccc12)c1ccc(cc1)S(=O)(=O)Nc1ccccc1

InChI Key: InChIKey=SHNGMJIXFFGIPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152644 (4-(1,3-Dioxoisoindolin-2-yl)-N-phenylbenzenesulpho...) Show SMILES O=C1N(C(=O)c2ccccc12)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C30H22Br2N4S/c31-19-8-12-27-23(14-19)25(16-33-27)29(26-17-34-28-13-9-20(32)15-24(26)28)18-6-10-22(11-7-18)36-30(37)35-21-4-2-1-3-5-21/h1-17,29,33-34H,(H2,35,36,37)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
					More data for this Ligand-Target Pair