BDBM152645 4-(1,3-Dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)benzenesulphonamide (8)

SMILES: Oc1ccccc1NS(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=STLFFYKEPSYTDE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152645 (4-(1,3-Dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)be...) Show SMILES Oc1ccccc1NS(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C27H22Br2N4O2S/c1-2-35-27(34)33-26(36)32-18-7-3-15(4-8-18)25(21-13-30-23-9-5-16(28)11-19(21)23)22-14-31-24-10-6-17(29)12-20(22)24/h3-14,25,30-31H,2H2,1H3,(H2,32,33,34,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
					More data for this Ligand-Target Pair