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SMILES: [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6])-[#8]-[#6](=O)-[#7]-1-[#6]-[#6](-[#6]-1)-[#8]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]C(F)(F)F)-[#6]-[#6]-1

InChI Key: InChIKey=GLHKMILNYHIGPM-RUNZLFIYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152658   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM152658 (US10023561, Example 81 | US9682965, 81) Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6])-[#8]-[#6](=O)-[#7]-1-[#6]-[#6](-[#6]-1)-[#8]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]C(F)(F)F)-[#6]-[#6]-1 |r| Show InChI InChI=1S/C27H40F3N3O7/c1-17(2)5-6-20-25(3,40-20)22-21(36-4)19(7-8-26(22)16-37-26)39-24(35)33-13-18(14-33)38-23(34)32-11-9-31(10-12-32)15-27(28,29)30/h5,18-22H,6-16H2,1-4H3/t19-,20-,21-,22-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	275	n/a	n/a	n/a	n/a	7.4	n/a
Zafgen, Inc. US Patent					Assay Description The plate was sealed with a TopSeal A cover and mixed briefly on an orbital mixer at 900 rpm. The plate was incubated for a further 25 minutes at 25Â...				US Patent US10023561 (2018) BindingDB Entry DOI: 10.7270/Q23F4RQ2
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM152658 (US10023561, Example 81 | US9682965, 81) Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6])-[#8]-[#6](=O)-[#7]-1-[#6]-[#6](-[#6]-1)-[#8]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]C(F)(F)F)-[#6]-[#6]-1 |r| Show InChI InChI=1S/C27H40F3N3O7/c1-17(2)5-6-20-25(3,40-20)22-21(36-4)19(7-8-26(22)16-37-26)39-24(35)33-13-18(14-33)38-23(34)32-11-9-31(10-12-32)15-27(28,29)30/h5,18-22H,6-16H2,1-4H3/t19-,20-,21-,22-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	275	n/a	n/a	n/a	n/a	7.4	n/a
Zafgen, Inc. US Patent					Assay Description Flag tagged Human recombinant MetAP2 expressed and isolated for use as the enzyme source. 10 mM stock solutions of compounds were prepared in 100% DM...				US Patent US9682965 (2017) BindingDB Entry DOI: 10.7270/Q29S1P74
					More data for this Ligand-Target Pair