BDBM152758 US10023561, Example 122::US9682965, 122

SMILES: [#6]-[#6]-[#7]-[#6]-[#6@@H]-1-[#6]-[#6]-[#7]-1-[#6](=O)-[#8]-[#6@@H]-1-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H](-[#6@@H]-1-[#8]-[#6])[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key: InChIKey=YCRVONHMVAIRQX-AXGJTTQDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM152758 (US10023561, Example 122 | US9682965, 122) Show SMILES [#6]-[#6]-[#7]-[#6]-[#6@@H]-1-[#6]-[#6]-[#7]-1-[#6](=O)-[#8]-[#6@@H]-1-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H](-[#6@@H]-1-[#8]-[#6])[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6] |r| Show InChI InChI=1S/C23H38N2O5/c1-6-24-13-16-10-12-25(16)21(26)29-17-9-11-23(14-28-23)20(19(17)27-5)22(4)18(30-22)8-7-15(2)3/h7,16-20,24H,6,8-14H2,1-5H3/t16-,17+,18+,19+,20+,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.4	n/a
Zafgen, Inc. US Patent					Assay Description The plate was sealed with a TopSeal A cover and mixed briefly on an orbital mixer at 900 rpm. The plate was incubated for a further 25 minutes at 25Â...				US Patent US10023561 (2018) BindingDB Entry DOI: 10.7270/Q23F4RQ2
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM152758 (US10023561, Example 122 | US9682965, 122) Show SMILES [#6]-[#6]-[#7]-[#6]-[#6@@H]-1-[#6]-[#6]-[#7]-1-[#6](=O)-[#8]-[#6@@H]-1-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H](-[#6@@H]-1-[#8]-[#6])[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6] |r| Show InChI InChI=1S/C23H38N2O5/c1-6-24-13-16-10-12-25(16)21(26)29-17-9-11-23(14-28-23)20(19(17)27-5)22(4)18(30-22)8-7-15(2)3/h7,16-20,24H,6,8-14H2,1-5H3/t16-,17+,18+,19+,20+,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.4	n/a
Zafgen, Inc. US Patent					Assay Description Flag tagged Human recombinant MetAP2 expressed and isolated for use as the enzyme source. 10 mM stock solutions of compounds were prepared in 100% DM...				US Patent US9682965 (2017) BindingDB Entry DOI: 10.7270/Q29S1P74
					More data for this Ligand-Target Pair