BDBM152773 4-(3-Morpholinopropoxy)-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide (12a)

SMILES: Oc1cc(OCCCN2CCOCC2)ccc1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=USCNGGLGTJXIDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EGFR (Homo sapiens (Human))	BDBM152773 (4-(3-Morpholinopropoxy)-N-(3-chloro-4-fluorophenyl...) Show SMILES Oc1cc(OCCCN2CCOCC2)ccc1C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C20H22ClFN2O4/c21-17-12-14(2-5-18(17)22)23-20(26)16-4-3-15(13-19(16)25)28-9-1-6-24-7-10-27-11-8-24/h2-5,12-13,25H,1,6-11H2,(H,23,26)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	25
Anhui University of Chinese Medicine					Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...				Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR
					More data for this Ligand-Target Pair