BDBM152781 1-[(2-chloro-5-methylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride (1)

SMILES: Cl.COc1ccccc1N1CCN(CCCOc2cc(C)ccc2Cl)CC1

InChI Key: InChIKey=IYKSSWZHPWGAON-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152781 (1-[(2-chloro-5-methylphenoxy)propyl]-4-(2-methoxyp...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)ccc2Cl)CC1 Show InChI InChI=1S/C21H27ClN2O2.ClH/c1-17-8-9-18(22)21(16-17)26-15-5-10-23-11-13-24(14-12-23)19-6-3-4-7-20(19)25-2;/h3-4,6-9,16H,5,10-15H2,1-2H3;1H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	-10.7	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair