BDBM152809 US8993568, 5

SMILES: CS(=O)(=O)N[C@@H](c1ccc(CN2CCOC(C2)c2ccccc2Cl)cc1)C(F)(F)F

InChI Key: InChIKey=IZSIOYYUIHWQLI-GGYWPGCISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM152809 (US8993568, 5) Show SMILES CS(=O)(=O)N[C@@H](c1ccc(CN2CCOC(C2)c2ccccc2Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C20H22ClF3N2O3S/c1-30(27,28)25-19(20(22,23)24)15-8-6-14(7-9-15)12-26-10-11-29-18(13-26)16-4-2-3-5-17(16)21/h2-9,18-19,25H,10-13H2,1H3/t18?,19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
					More data for this Ligand-Target Pair