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SMILES: CCc1ncc(o1)C(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F

InChI Key: InChIKey=JCOUIVSPKZYRHL-MRXNPFEDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153106   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Membrane metallo-endopeptidase-like 1


(Homo sapiens (Human))		BDBM153106
PNG
(US8993631, 9-7)
Show SMILES CCc1ncc(o1)C(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r|
Show InChI InChI=1S/C22H20ClFN2O4/c1-2-20-25-12-19(30-20)22(29)26-16(11-21(27)28)9-13-3-5-14(6-4-13)17-10-15(23)7-8-18(17)24/h3-8,10,12,16H,2,9,11H2,1H3,(H,26,29)(H,27,28)/t16-/m1/s1
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 0.400n/an/an/an/a7.425



Novartis AG

US Patent


Assay Description
Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...

US Patent US8993631 (2015)


BindingDB Entry DOI: 10.7270/Q20C4THK
More data for this
Ligand-Target Pair