BDBM15397 3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide::3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamide 14l

SMILES: Oc1cc(O)c(cc1Cl)-c1n[nH]cc1C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=KSQXYHCHSNPQNL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM15397 (3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-fluoropheny...) Show SMILES Oc1cc(O)c(cc1Cl)-c1n[nH]cc1C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C17H13ClFN3O3/c18-13-5-11(14(23)6-15(13)24)16-12(8-21-22-16)17(25)20-7-9-1-3-10(19)4-2-9/h1-6,8,23-24H,7H2,(H,20,25)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.35E+3	n/a	n/a	n/a	n/a	7.4	22
Vernalis (R&D) Ltd					Assay Description The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...				Bioorg Med Chem Lett 15: 5197-201 (2005) Article DOI: 10.1016/j.bmcl.2005.08.091 BindingDB Entry DOI: 10.7270/Q2N58JND
					More data for this Ligand-Target Pair