BDBM154541 N-allyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxamide (JW1043)

SMILES: Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(=O)NCC=C

InChI Key: InChIKey=BFUFFOZARDSFAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 154541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2) (Mus musculus (Mouse))	BDBM154541 (N-allyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tos...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(=O)NCC=C |c:10| Show InChI InChI=1S/C33H38N2O3S/c1-7-22-34-32(36)29-20-21-30(25-12-8-23(2)9-13-25)35(39(37,38)28-18-10-24(3)11-19-28)31(29)26-14-16-27(17-15-26)33(4,5)6/h7-20,30-31H,1,21-22H2,2-6H3,(H,34,36)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
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