BDBM154924 US9000029, 3

SMILES: COc1cccc(c1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cccc(SC)c1

InChI Key: InChIKey=MENYSNIOINZHOK-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM154924 (US9000029, 3) Show SMILES COc1cccc(c1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cccc(SC)c1 Show InChI InChI=1S/C19H22N2O4S2/c1-25-15-7-4-9-17(13-15)27(23,24)21-11-5-10-18(21)19(22)20-14-6-3-8-16(12-14)26-2/h3-4,6-9,12-13,18H,5,10-11H2,1-2H3,(H,20,22)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM154924 (US9000029, 3) Show SMILES COc1cccc(c1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cccc(SC)c1 Show InChI InChI=1S/C19H22N2O4S2/c1-25-15-7-4-9-17(13-15)27(23,24)21-11-5-10-18(21)19(22)20-14-6-3-8-16(12-14)26-2/h3-4,6-9,12-13,18H,5,10-11H2,1-2H3,(H,20,22)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair