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SMILES: N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CCCC1

InChI Key: InChIKey=BDCLWTLCIGPXMA-PXAZEXFGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15520   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM15520
PNG
((3R, 4R)-1-(6-(pyrrolidin-1-yl)pyrimidin-4-yl)-4-(...)
Show SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CCCC1 |r|
Show InChI InChI=1S/C19H22F3N5/c20-14-8-16(22)15(21)7-13(14)12-3-6-27(10-17(12)23)19-9-18(24-11-25-19)26-4-1-2-5-26/h7-9,11-12,17H,1-6,10,23H2/t12-,17+/m1/s1
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MMDB

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Similars
Article
PubMed
 2.30n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...

J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
BindingDB Entry DOI: 10.7270/Q2VQ30XV
More data for this
Ligand-Target Pair