BDBM15524 (3R)-1-{6-[(3R,4R)-3-amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]pyrimidin-4-yl}pyrrolidin-3-ol::(R)-1-(6-((3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl)pyrimidin-4-yl)pyrrolidin-3-ol::Piperidine-Constrained Phenethylamine 48

SMILES: N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CC[C@@H](O)C1

InChI Key: InChIKey=OOJZORPUAPQAAZ-QFSBIZTOSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM15524 ((3R)-1-{6-[(3R,4R)-3-amino-4-(2,4,5-trifluoropheny...) Show SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C19H22F3N5O/c20-14-6-16(22)15(21)5-13(14)12-2-4-27(9-17(12)23)19-7-18(24-10-25-19)26-3-1-11(28)8-26/h5-7,10-12,17,28H,1-4,8-9,23H2/t11-,12-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...				J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM15524 ((3R)-1-{6-[(3R,4R)-3-amino-4-(2,4,5-trifluoropheny...) Show SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C19H22F3N5O/c20-14-6-16(22)15(21)5-13(14)12-2-4-27(9-17(12)23)19-7-18(24-10-25-19)26-3-1-11(28)8-26/h5-7,10-12,17,28H,1-4,8-9,23H2/t11-,12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...				J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM15524 ((3R)-1-{6-[(3R,4R)-3-amino-4-(2,4,5-trifluoropheny...) Show SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C19H22F3N5O/c20-14-6-16(22)15(21)5-13(14)12-2-4-27(9-17(12)23)19-7-18(24-10-25-19)26-3-1-11(28)8-26/h5-7,10-12,17,28H,1-4,8-9,23H2/t11-,12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...				J Med Chem 50: 1983-7 (2007) Article DOI: 10.1021/jm061436d BindingDB Entry DOI: 10.7270/Q2VQ30XV
					More data for this Ligand-Target Pair