BDBM155392 US9006283, 2
SMILES: CCOC(=O)c1c(NC(=O)C(=O)N\N=C\c2cccc(OC)c2O)sc2CC(C)CCc12
InChI Key: InChIKey=WQNLUIKFBJMWTA-FOKLQQMPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-amyloid protein 42 (Rattus norvegicus (Rat)) | BDBM155392 (US9006283, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Acumen Pharmaceuticals, Inc. US Patent | Assay Description In this assay, assembly of Abeta 1-42 oligomer formation is monitored by FRET using N-terminal conjugates of fluorescein-Abeta 1-42 as both the donor... | US Patent US9006283 (2015) BindingDB Entry DOI: 10.7270/Q24T6H3Z | |||||||||||
More data for this Ligand-Target Pair |