BDBM155393 US9006283, 3

SMILES: CCOC(=O)c1c(NC(=O)C(=O)N\N=C\c2c(O)ccc3ccccc23)sc2CC(C)CCc12

InChI Key: InChIKey=HTSXWHGXQOLKRU-LGJNPRDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-amyloid protein 42 (Rattus norvegicus (Rat))	BDBM155393 (US9006283, 3) Show SMILES CCOC(=O)c1c(NC(=O)C(=O)N\N=C\c2c(O)ccc3ccccc23)sc2CC(C)CCc12 Show InChI InChI=1S/C25H25N3O5S/c1-3-33-25(32)21-17-10-8-14(2)12-20(17)34-24(21)27-22(30)23(31)28-26-13-18-16-7-5-4-6-15(16)9-11-19(18)29/h4-7,9,11,13-14,29H,3,8,10,12H2,1-2H3,(H,27,30)(H,28,31)/b26-13+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	8.0	37
Acumen Pharmaceuticals, Inc. US Patent					Assay Description In this assay, assembly of Abeta 1-42 oligomer formation is monitored by FRET using N-terminal conjugates of fluorescein-Abeta 1-42 as both the donor...				US Patent US9006283 (2015) BindingDB Entry DOI: 10.7270/Q24T6H3Z
					More data for this Ligand-Target Pair