BDBM155395 US9006283, 5

SMILES: COc1ccccc1NC(=O)C(=O)N1N=C(CC(C)C)CC1(O)C(F)(F)F

InChI Key: InChIKey=HYCRMNNPAJWJGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-amyloid protein 42 (Rattus norvegicus (Rat))	BDBM155395 (US9006283, 5) Show SMILES COc1ccccc1NC(=O)C(=O)N1N=C(CC(C)C)CC1(O)C(F)(F)F |t:15| Show InChI InChI=1S/C17H20F3N3O4/c1-10(2)8-11-9-16(26,17(18,19)20)23(22-11)15(25)14(24)21-12-6-4-5-7-13(12)27-3/h4-7,10,26H,8-9H2,1-3H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	8.0	37
Acumen Pharmaceuticals, Inc. US Patent					Assay Description In this assay, assembly of Abeta 1-42 oligomer formation is monitored by FRET using N-terminal conjugates of fluorescein-Abeta 1-42 as both the donor...				US Patent US9006283 (2015) BindingDB Entry DOI: 10.7270/Q24T6H3Z
					More data for this Ligand-Target Pair