BDBM155438 US9006454, I75

SMILES: Cc1cc(C(O)=O)c2[nH]c(nc2c1)-c1ccc(nc1)-c1ccccc1

InChI Key: InChIKey=MLYJJISQOFFZCT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM155438 (US9006454, I75) Show SMILES Cc1cc(C(O)=O)c2[nH]c(nc2c1)-c1ccc(nc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O2/c1-12-9-15(20(24)25)18-17(10-12)22-19(23-18)14-7-8-16(21-11-14)13-5-3-2-4-6-13/h2-11H,1H3,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	8.0	n/a
Merck Serono S.A. US Patent					Assay Description The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...				US Patent US9006454 (2015) BindingDB Entry DOI: 10.7270/Q2125RCJ
					More data for this Ligand-Target Pair