BDBM156175 US9018214, 226

SMILES: C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(cc23)C(F)(F)C2CCC2)[C@@H](CN2CCCC2=O)CN1

InChI Key: InChIKey=DBKVIBHYJAQLIJ-YLJYHZDGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM156175 (US9018214, 226) Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(cc23)C(F)(F)C2CCC2)[C@@H](CN2CCCC2=O)CN1 |r| Show InChI InChI=1S/C26H37F2N5O2/c1-17-13-32(20(12-29-17)14-31-9-5-8-22(31)34)15-23(35)33-16-25(2,3)24-21(33)10-19(11-30-24)26(27,28)18-6-4-7-18/h10-11,17-18,20,29H,4-9,12-16H2,1-3H3/t17-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	25
Astex Therapeutics Limited US Patent					Assay Description Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...				US Patent US9018214 (2015) BindingDB Entry DOI: 10.7270/Q23T9FXQ
					More data for this Ligand-Target Pair
X-linked inhibitor of apoptosis protein (XIAP) (Homo sapiens (Human))	BDBM156175 (US9018214, 226) Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(cc23)C(F)(F)C2CCC2)[C@@H](CN2CCCC2=O)CN1 |r| Show InChI InChI=1S/C26H37F2N5O2/c1-17-13-32(20(12-29-17)14-31-9-5-8-22(31)34)15-23(35)33-16-25(2,3)24-21(33)10-19(11-30-24)26(27,28)18-6-4-7-18/h10-11,17-18,20,29H,4-9,12-16H2,1-3H3/t17-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	7.5	25
Astex Therapeutics Limited US Patent					Assay Description Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...				US Patent US9018214 (2015) BindingDB Entry DOI: 10.7270/Q23T9FXQ
					More data for this Ligand-Target Pair