BDBM15619 4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((1-ethylpyrrolidin-2-yl)methyl)-1H-pyrrole-2-carboxamide::4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-[(1-ethylpyrrolidin-2-yl)methyl]-1H-pyrrole-2-carboxamide::Pyrrole Carboxamide Analog 5e

SMILES: CCN1CCCC1CNC(=O)c1cc(c[nH]1)-c1n[nH]cc1-c1cccc(Cl)c1

InChI Key: InChIKey=FYNXWPSWTKNQFN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM15619 (4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((1-ethyl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(c[nH]1)-c1n[nH]cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C21H24ClN5O/c1-2-27-8-4-7-17(27)12-24-21(28)19-10-15(11-23-19)20-18(13-25-26-20)14-5-3-6-16(22)9-14/h3,5-6,9-11,13,17,23H,2,4,7-8,12H2,1H3,(H,24,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex					Assay Description A coupled spectrophotometric assay was used in which ADP generated by JNK3 was converted to ATP by pyruvate kinase with the production of pyruvate fr...				J Med Chem 50: 1280-7 (2007) Article DOI: 10.1021/jm061381f BindingDB Entry DOI: 10.7270/Q2BR8QFV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM15619 (4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((1-ethyl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(c[nH]1)-c1n[nH]cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C21H24ClN5O/c1-2-27-8-4-7-17(27)12-24-21(28)19-10-15(11-23-19)20-18(13-25-26-20)14-5-3-6-16(22)9-14/h3,5-6,9-11,13,17,23H,2,4,7-8,12H2,1H3,(H,24,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	>-6.93	n/a	n/a	n/a	n/a	n/a	7.5	30
Vertex					Assay Description A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...				J Med Chem 50: 1280-7 (2007) Article DOI: 10.1021/jm061381f BindingDB Entry DOI: 10.7270/Q2BR8QFV
					More data for this Ligand-Target Pair