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SMILES: Cc1cc(C)n2nc(SCc3nc(cn3C)-c3ccccc3F)nc2c1

InChI Key: InChIKey=QOODWVLFSVPCDI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156290 (US9018217, 2-[4-(2-Fluoro-phenyl)-1-methyl-1H-imid...) Show SMILES Cc1cc(C)n2nc(SCc3nc(cn3C)-c3ccccc3F)nc2c1 Show InChI InChI=1S/C19H18FN5S/c1-12-8-13(2)25-17(9-12)22-19(23-25)26-11-18-21-16(10-24(18)3)14-6-4-5-7-15(14)20/h4-10H,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156290 (US9018217, 2-[4-(2-Fluoro-phenyl)-1-methyl-1H-imid...) Show SMILES Cc1cc(C)n2nc(SCc3nc(cn3C)-c3ccccc3F)nc2c1 Show InChI InChI=1S/C19H18FN5S/c1-12-8-13(2)25-17(9-12)22-19(23-25)26-11-18-21-16(10-24(18)3)14-6-4-5-7-15(14)20/h4-10H,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair