BDBM156356 US9018217, 7-Isopropyl-5-methyl-2-[2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine::US9592230, 7-Isopropyl-5-methyl-2-[2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine

SMILES: CC(C)c1cc(C)nc2nc(CCc3nc(cn3C)-c3ccccc3)nn12

InChI Key: InChIKey=IAWFRMLXGRQFIJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156356 (US9018217, 7-Isopropyl-5-methyl-2-[2-(1-methyl-4-p...) Show SMILES CC(C)c1cc(C)nc2nc(CCc3nc(cn3C)-c3ccccc3)nn12 Show InChI InChI=1S/C21H24N6/c1-14(2)18-12-15(3)22-21-24-19(25-27(18)21)10-11-20-23-17(13-26(20)4)16-8-6-5-7-9-16/h5-9,12-14H,10-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156356 (US9018217, 7-Isopropyl-5-methyl-2-[2-(1-methyl-4-p...) Show SMILES CC(C)c1cc(C)nc2nc(CCc3nc(cn3C)-c3ccccc3)nn12 Show InChI InChI=1S/C21H24N6/c1-14(2)18-12-15(3)22-21-24-19(25-27(18)21)10-11-20-23-17(13-26(20)4)16-8-6-5-7-9-16/h5-9,12-14H,10-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair