BDBM156547 US10118915, Compound 328::US9682966, 328

SMILES: Cc1nc(no1)-c1cc2cc(C)ccc2nc1N1CCC(NC2CCCCC2)C(CO)C1

InChI Key: InChIKey=FQLBPYJFBZMVLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156547 (US10118915, Compound 328 | US9682966, 328) Show SMILES Cc1nc(no1)-c1cc2cc(C)ccc2nc1N1CCC(NC2CCCCC2)C(CO)C1 Show InChI InChI=1S/C25H33N5O2/c1-16-8-9-22-18(12-16)13-21(24-26-17(2)32-29-24)25(28-22)30-11-10-23(19(14-30)15-31)27-20-6-4-3-5-7-20/h8-9,12-13,19-20,23,27,31H,3-7,10-11,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description Well-known assay for kappa opioid receptor				US Patent US10118915 (2018) BindingDB Entry DOI: 10.7270/Q23J3G00
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156547 (US10118915, Compound 328 | US9682966, 328) Show SMILES Cc1nc(no1)-c1cc2cc(C)ccc2nc1N1CCC(NC2CCCCC2)C(CO)C1 Show InChI InChI=1S/C25H33N5O2/c1-16-8-9-22-18(12-16)13-21(24-26-17(2)32-29-24)25(28-22)30-11-10-23(19(14-30)15-31)27-20-6-4-3-5-7-20/h8-9,12-13,19-20,23,27,31H,3-7,10-11,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute US Patent					Assay Description The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...				US Patent US9682966 (2017) BindingDB Entry DOI: 10.7270/Q2610XHQ
					More data for this Ligand-Target Pair