BDBM15716 (5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)phenylmethanone::4-benzoyl-3-methyl-1-phenyl-1H-pyrazol-5-ol::pyrazole 3

SMILES: Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)c1ccccc1

InChI Key: InChIKey=KJTRXVXWSSPHRV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15716 ((5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)pheny...) Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)c1ccccc1 Show InChI InChI=1S/C17H14N2O2/c1-12-15(16(20)13-8-4-2-5-9-13)17(21)19(18-12)14-10-6-3-7-11-14/h2-11,18H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair