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SMILES: CC(N1CCOCC1)n1c(c(-c2ccc(F)cc2)c2ncccc12)-c1ccncc1

InChI Key: InChIKey=SAFJFWSNEFJDPZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15768   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM15768
PNG
(3-(4-Fluorophenyl)-1-morpholinoethyl-2-pyridin-4-y...)
Show SMILES CC(N1CCOCC1)n1c(c(-c2ccc(F)cc2)c2ncccc12)-c1ccncc1
Show InChI InChI=1S/C24H23FN4O/c1-17(28-13-15-30-16-14-28)29-21-3-2-10-27-23(21)22(18-4-6-20(25)7-5-18)24(29)19-8-11-26-12-9-19/h2-12,17H,13-16H2,1H3
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Article
PubMed
n/an/a 185n/an/an/an/a7.430



Roche Palo Alto LLC



Assay Description
Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...

J Med Chem 46: 4702-13 (2003)


Article DOI: 10.1021/jm0301787
BindingDB Entry DOI: 10.7270/Q2ZG6QHT
More data for this
Ligand-Target Pair