null

SMILES: CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1

InChI Key: InChIKey=XXVYMALEOOTBKD-HXUWFJFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 158141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enteropeptidase (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.720	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
AJINOMOTO CO., INC. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...				US Patent US9227949 (2016) BindingDB Entry DOI: 10.7270/Q2959GBT
					More data for this Ligand-Target Pair
Enteropeptidase (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EA Pharma Co., Ltd. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...				US Patent US9655879 (2017) BindingDB Entry DOI: 10.7270/Q22Z17KS
					More data for this Ligand-Target Pair
Enteropeptidase (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.720	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
Ajinomoto Co., Inc. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...				US Patent US9024044 (2015) BindingDB Entry DOI: 10.7270/Q2F47MVB
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EA Pharma Co., Ltd. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...				US Patent US9655879 (2017) BindingDB Entry DOI: 10.7270/Q22Z17KS
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.14	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
AJINOMOTO CO., INC. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...				US Patent US9227949 (2016) BindingDB Entry DOI: 10.7270/Q2959GBT
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM158141 (US9024044, 69 | US9227949, 69 | US9655879, 69) Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.14	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
Ajinomoto Co., Inc. US Patent					Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...				US Patent US9024044 (2015) BindingDB Entry DOI: 10.7270/Q2F47MVB
					More data for this Ligand-Target Pair