BDBM158386 US9029381, 28

SMILES: Brc1cccc(c1)C1CC1C(=O)N1CCN(CC1)C1CCC1

InChI Key: InChIKey=FRDKWOZDEHJOMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM158386 (US9029381, 28) Show SMILES Brc1cccc(c1)C1CC1C(=O)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C18H23BrN2O/c19-14-4-1-3-13(11-14)16-12-17(16)18(22)21-9-7-20(8-10-21)15-5-2-6-15/h1,3-4,11,15-17H,2,5-10,12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.37	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca AB US Patent					Assay Description The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...				US Patent US9029381 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BDG
					More data for this Ligand-Target Pair