BDBM158387 US9029381, 29
SMILES: O=C(C1CC1c1cccc(c1)C#N)N1CCN(CC1)C1CCC1
InChI Key: InChIKey=JKPJWTDIXZCJPK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM158387 (US9029381, 29) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.834 | n/a | n/a | n/a | n/a | n/a | n/a |
Astrazeneca AB US Patent | Assay Description The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]... | US Patent US9029381 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BDG | |||||||||||
More data for this Ligand-Target Pair |