BDBM158446 US9029399, 20A::US9339501, 20A

SMILES: Clc1cc2cc(ccc2s1)N1CCN(C1=O)c1cnccc1C1CC1

InChI Key: InChIKey=IJLNPQPMWBWCDQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM158446 (US9029399, 20A | US9339501, 20A) Show SMILES Clc1cc2cc(ccc2s1)N1CCN(C1=O)c1cnccc1C1CC1 Show InChI InChI=1S/C19H16ClN3OS/c20-18-10-13-9-14(3-4-17(13)25-18)22-7-8-23(19(22)24)16-11-21-6-5-15(16)12-1-2-12/h3-6,9-12H,1-2,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...				US Patent US9339501 (2016) BindingDB Entry DOI: 10.7270/Q26T0KG2
					More data for this Ligand-Target Pair
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM158446 (US9029399, 20A | US9339501, 20A) Show SMILES Clc1cc2cc(ccc2s1)N1CCN(C1=O)c1cnccc1C1CC1 Show InChI InChI=1S/C19H16ClN3OS/c20-18-10-13-9-14(3-4-17(13)25-18)22-7-8-23(19(22)24)16-11-21-6-5-15(16)12-1-2-12/h3-6,9-12H,1-2,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...				US Patent US9029399 (2015) BindingDB Entry DOI: 10.7270/Q28G8JFD
					More data for this Ligand-Target Pair