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SMILES: COc1cccc(c1)-n1c(cc2ccccc12)C(=O)NC1CCN(CC1)C(C)C

InChI Key: InChIKey=BVSIBCJUGIVAKQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM15850
PNG
(1-(3-methoxyphenyl)-N-[1-(propan-2-yl)piperidin-4-...)
Show SMILES COc1cccc(c1)-n1c(cc2ccccc12)C(=O)NC1CCN(CC1)C(C)C
Show InChI InChI=1S/C24H29N3O2/c1-17(2)26-13-11-19(12-14-26)25-24(28)23-15-18-7-4-5-10-22(18)27(23)20-8-6-9-21(16-20)29-3/h4-10,15-17,19H,11-14H2,1-3H3,(H,25,28)
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Article
PubMed
 2.48E+3 -7.64n/an/an/an/an/a7.825



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...

Bioorg Med Chem Lett 14: 4191-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.020
BindingDB Entry DOI: 10.7270/Q22805WQ
More data for this
Ligand-Target Pair