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BDBM158532 US9034866, 7

SMILES: Cc1cc(no1)[C@](C)(O)C#Cc1ccc2OCCc3sc(nc3-c2c1)C(N)=O

InChI Key: InChIKey=ZOVBNYKQIZBMBY-GNLPSFAGNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158532   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NF-kappa-beta-inducing kinase (NF-kB)


(Homo sapiens (Human))
BDBM158532
PNG
(US9034866, 7)
Show SMILES Cc1cc(no1)[C@](C)(O)C#Cc1ccc2OCCc3sc(nc3-c2c1)C(N)=O |r|
Show InChI InChI=1/C20H17N3O4S/c1-11-9-16(23-27-11)20(2,25)7-5-12-3-4-14-13(10-12)17-15(6-8-26-14)28-19(22-17)18(21)24/h3-4,9-10,25H,6,8H2,1-2H3,(H2,21,24)/t20-/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.200n/an/an/an/an/an/a7.2n/a



Genentech, Inc.

US Patent


Assay Description
The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...


US Patent US9034866 (2015)


BindingDB Entry DOI: 10.7270/Q2GX49B0
More data for this
Ligand-Target Pair