BDBM158610 US9034866, 85

SMILES: CC(C)(O)C#Cc1cc2-c3nc(C(N)=O)c(C(=O)NCC#N)n3CCOc2cc1F

InChI Key: InChIKey=CMPNUAYWOMEUPJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM158610 (US9034866, 85) Show SMILES CC(C)(O)C#Cc1cc2-c3nc(C(N)=O)c(C(=O)NCC#N)n3CCOc2cc1F Show InChI InChI=1S/C20H18FN5O4/c1-20(2,29)4-3-11-9-12-14(10-13(11)21)30-8-7-26-16(19(28)24-6-5-22)15(17(23)27)25-18(12)26/h9-10,29H,6-8H2,1-2H3,(H2,23,27)(H,24,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...				US Patent US9034866 (2015) BindingDB Entry DOI: 10.7270/Q2GX49B0
					More data for this Ligand-Target Pair